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SMILES: CN(C)CCOc1ccc(cc1)-c1cc2ccccc2c(=O)[nH]1

InChI Key: InChIKey=DYTWWNXGCKCQJS-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 192905   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Poly [ADP-ribose] polymerase tankyrase-1 [1068-1325]


(Homo sapiens (Human))		BDBM192905
PNG
(US9193689, REF-5)
Show SMILES CN(C)CCOc1ccc(cc1)-c1cc2ccccc2c(=O)[nH]1
Show InChI InChI=1S/C19H20N2O2/c1-21(2)11-12-23-16-9-7-14(8-10-16)18-13-15-5-3-4-6-17(15)19(22)20-18/h3-10,13H,11-12H2,1-2H3,(H,20,22)
PDB

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PC sid
UniChem

Similars
US Patent
n/an/a 17n/an/an/an/an/an/a



INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (THE)

US Patent


Assay Description
Tankyrase activity was assayed using a 96-well format HT Universal Chemiluminescent PARP Assay Kit (Trevigen, Inc, cat. no. 4676-096-K) according to ...

US Patent US9193689 (2015)


BindingDB Entry DOI: 10.7270/Q29S1PTR
More data for this
Ligand-Target Pair