BDBM193126 US9193736, 42

SMILES: CC(=O)NS(=O)(=O)c1ccc(cc1)-c1c(CCc2ccc3ccccc3n2)nc2c(ccnn12)N1CCOCC1

InChI Key: InChIKey=GAZVVLJOQPSZNU-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 193126   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 10A (PDE10A2) (Homo sapiens (Human))	BDBM193126 (US9193736, 42) Show SMILES CC(=O)NS(=O)(=O)c1ccc(cc1)-c1c(CCc2ccc3ccccc3n2)nc2c(ccnn12)N1CCOCC1 Show InChI InChI=1S/C29H28N6O4S/c1-20(36)33-40(37,38)24-11-7-22(8-12-24)28-26(13-10-23-9-6-21-4-2-3-5-25(21)31-23)32-29-27(14-15-30-35(28)29)34-16-18-39-19-17-34/h2-9,11-12,14-15H,10,13,16-19H2,1H3,(H,33,36)	PDB GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica, NV US Patent					Assay Description Human recombinant PDE10A2 was expressed in Sf9 cells, using a recombinant baculovirus construct containing the full length sequence containing a 6ÿH...				US Patent US9193736 (2015) BindingDB Entry DOI: 10.7270/Q2XK8DCS
					More data for this Ligand-Target Pair
Phosphodiesterase Type 10 (PDE10A) (Rattus norvegicus (rat))	BDBM193126 (US9193736, 42) Show SMILES CC(=O)NS(=O)(=O)c1ccc(cc1)-c1c(CCc2ccc3ccccc3n2)nc2c(ccnn12)N1CCOCC1 Show InChI InChI=1S/C29H28N6O4S/c1-20(36)33-40(37,38)24-11-7-22(8-12-24)28-26(13-10-23-9-6-21-4-2-3-5-25(21)31-23)32-29-27(14-15-30-35(28)29)34-16-18-39-19-17-34/h2-9,11-12,14-15H,10,13,16-19H2,1H3,(H,33,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.8	n/a
Janssen Pharmaceutica, NV US Patent					Assay Description Rat recombinant PDE10a (rPDE10a) was expressed in Sf9 cells using a recombinant rPDE10a baculovirus construct. Cells were harvested after 48 h of inf...				US Patent US9193736 (2015) BindingDB Entry DOI: 10.7270/Q2XK8DCS
					More data for this Ligand-Target Pair