BDBM194126 US9200001, 42

SMILES: COc1ccc(Cc2nc(C)nn2-c2cc(nc(C)n2)C2CC2c2cc3CCCn3n2)cc1OC

InChI Key: InChIKey=PHEHYDFIWORXNN-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 194126   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 10A (PDE10A2) (Homo sapiens (Human))	BDBM194126 (US9200001, 42) Show SMILES COc1ccc(Cc2nc(C)nn2-c2cc(nc(C)n2)C2CC2c2cc3CCCn3n2)cc1OC Show InChI InChI=1S/C26H29N7O2/c1-15-27-21(19-13-20(19)22-12-18-6-5-9-32(18)31-22)14-26(28-15)33-25(29-16(2)30-33)11-17-7-8-23(34-3)24(10-17)35-4/h7-8,10,12,14,19-20H,5-6,9,11,13H2,1-4H3	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description In a typical experiment the PDE10 inhibitory activity of the compounds of the present invention was determined in accordance with the following exp...				US Patent US9200001 (2015) BindingDB Entry DOI: 10.7270/Q2BP01M3
					More data for this Ligand-Target Pair