BDBM196788 US9212178, 17

SMILES: Cc1nn(cc1CN1C[C@H](O)CO1)-c1nc(Nc2ccc3n(C)cc(C(=O)C(F)(F)F)c3c2)ncc1Cl

InChI Key: InChIKey=DPOHUTMUGRCITM-HNNXBMFYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 196788   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM196788 (US9212178, 17) Show SMILES Cc1nn(cc1CN1C[C@H](O)CO1)-c1nc(Nc2ccc3n(C)cc(C(=O)C(F)(F)F)c3c2)ncc1Cl |r| Show InChI InChI=1S/C23H21ClF3N7O3/c1-12-13(7-33-9-15(35)11-37-33)8-34(31-12)21-18(24)6-28-22(30-21)29-14-3-4-19-16(5-14)17(10-32(19)2)20(36)23(25,26)27/h3-6,8,10,15,35H,7,9,11H2,1-2H3,(H,28,29,30)/t15-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	132	n/a	n/a	n/a	n/a	n/a	25
Genosco; Oscotec, Inc. US Patent					Assay Description Compounds of the invention were initially diluted to 10 mM in 100% DMSO (CALBIOCHEM) for storage and made into kinase buffer solution to create a com...				US Patent US9212178 (2015) BindingDB Entry DOI: 10.7270/Q2X9294C
					More data for this Ligand-Target Pair