BDBM196832 5-(4-fluorophenyl)-2-(((2-fluorophenyl)(methyl)amino)methyl)-6,7-dihydropyrazolo[1,5-a]pyrazin-4(5h)-one::US9676782, 83

SMILES: CN(Cc1cc2C(=O)N(CCn2n1)c1ccc(F)cc1)c1ccccc1F

InChI Key: InChIKey=BFMGYYXZYSVQBE-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 196832   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor (Rattus norvegicus (Rat))	BDBM196832 (5-(4-fluorophenyl)-2-(((2-fluorophenyl)(methyl)ami...) Show SMILES CN(Cc1cc2C(=O)N(CCn2n1)c1ccc(F)cc1)c1ccccc1F Show InChI InChI=1S/C20H18F2N4O/c1-24(18-5-3-2-4-17(18)22)13-15-12-19-20(27)25(10-11-26(19)23-15)16-8-6-14(21)7-9-16/h2-9,12H,10-11,13H2,1H3	PDB MMDB Reactome pathway KEGG B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	25
Vanderbilt University US Patent					Assay Description Gα15/TREx cells stably expressing rat mGlu3 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of a...				US Patent US9676782 (2017) BindingDB Entry DOI: 10.7270/Q2B8569W
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Rattus norvegicus (Rat))	BDBM196832 (5-(4-fluorophenyl)-2-(((2-fluorophenyl)(methyl)ami...) Show SMILES CN(Cc1cc2C(=O)N(CCn2n1)c1ccc(F)cc1)c1ccccc1F Show InChI InChI=1S/C20H18F2N4O/c1-24(18-5-3-2-4-17(18)22)13-15-12-19-20(27)25(10-11-26(19)23-15)16-8-6-14(21)7-9-16/h2-9,12H,10-11,13H2,1H3	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	876	n/a	n/a	n/a	n/a	n/a	25
Vanderbilt University US Patent					Assay Description HEK 293A cells stably expressing rat mGlu5 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of assay m...				US Patent US9676782 (2017) BindingDB Entry DOI: 10.7270/Q2B8569W
					More data for this Ligand-Target Pair