BDBM197336 R-TSA

SMILES: C[C@H](\C=C\C(=O)NO)\C=C(/C)C(=O)c1ccc(cc1)N(C)C

InChI Key: InChIKey=ALCVRKZFLFWUAZ-LSSUCPAZSA-N

Data: 12 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 197336   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
HDAC6 (CD1-CD2) (Danio rerio (Zebrafish))	BDBM197336 (R-TSA) Show SMILES C[C@H](\C=C\C(=O)NO)\C=C(/C)C(=O)c1ccc(cc1)N(C)C |r| Show InChI InChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-12,22H,1-4H3,(H,18,20)/b10-5+,13-11+/t12-/m1/s1	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.45	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Miescher Institute for Biomedical Research					Assay Description . Enzymatic characterization (Km determinations, Supplementary Fig. 3C) of zebrafish HDAC6 proteins (CD1-CD2; CD1H193A-CD2; CD1CD2H574A; CD1H193A- CD...				Nat Chem Biol 12: 748-54 (2016) Article DOI: 10.1038/nchembio.2140 BindingDB Entry DOI: 10.7270/Q2V986V6
					More data for this Ligand-Target Pair
Cereblon/Histone deacetylase 6 (Homo sapiens (Human))	BDBM197336 (R-TSA) Show SMILES C[C@H](\C=C\C(=O)NO)\C=C(/C)C(=O)c1ccc(cc1)N(C)C |r| Show InChI InChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-12,22H,1-4H3,(H,18,20)/b10-5+,13-11+/t12-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.67	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Miescher Institute for Biomedical Research					Assay Description . Enzymatic characterization (Km determinations, Supplementary Fig. 3C) of zebrafish HDAC6 proteins (CD1-CD2; CD1H193A-CD2; CD1CD2H574A; CD1H193A- CD...				Nat Chem Biol 12: 748-54 (2016) Article DOI: 10.1038/nchembio.2140 BindingDB Entry DOI: 10.7270/Q2V986V6
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM197336 (R-TSA) Show SMILES C[C@H](\C=C\C(=O)NO)\C=C(/C)C(=O)c1ccc(cc1)N(C)C |r| Show InChI InChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-12,22H,1-4H3,(H,18,20)/b10-5+,13-11+/t12-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.76	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Miescher Institute for Biomedical Research					Assay Description . Enzymatic characterization (Km determinations, Supplementary Fig. 3C) of zebrafish HDAC6 proteins (CD1-CD2; CD1H193A-CD2; CD1CD2H574A; CD1H193A- CD...				Nat Chem Biol 12: 748-54 (2016) Article DOI: 10.1038/nchembio.2140 BindingDB Entry DOI: 10.7270/Q2V986V6
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM197336 (R-TSA) Show SMILES C[C@H](\C=C\C(=O)NO)\C=C(/C)C(=O)c1ccc(cc1)N(C)C |r| Show InChI InChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-12,22H,1-4H3,(H,18,20)/b10-5+,13-11+/t12-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	17.8	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Miescher Institute for Biomedical Research					Assay Description . Enzymatic characterization (Km determinations, Supplementary Fig. 3C) of zebrafish HDAC6 proteins (CD1-CD2; CD1H193A-CD2; CD1CD2H574A; CD1H193A- CD...				Nat Chem Biol 12: 748-54 (2016) Article DOI: 10.1038/nchembio.2140 BindingDB Entry DOI: 10.7270/Q2V986V6
					More data for this Ligand-Target Pair
Histone deacetylase 3 (Homo sapiens (Human))	BDBM197336 (R-TSA) Show SMILES C[C@H](\C=C\C(=O)NO)\C=C(/C)C(=O)c1ccc(cc1)N(C)C |r| Show InChI InChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-12,22H,1-4H3,(H,18,20)/b10-5+,13-11+/t12-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.09	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Miescher Institute for Biomedical Research					Assay Description . Enzymatic characterization (Km determinations, Supplementary Fig. 3C) of zebrafish HDAC6 proteins (CD1-CD2; CD1H193A-CD2; CD1CD2H574A; CD1H193A- CD...				Nat Chem Biol 12: 748-54 (2016) Article DOI: 10.1038/nchembio.2140 BindingDB Entry DOI: 10.7270/Q2V986V6
					More data for this Ligand-Target Pair
Histone deacetylase 11 (Homo sapiens (Human))	BDBM197336 (R-TSA) Show SMILES C[C@H](\C=C\C(=O)NO)\C=C(/C)C(=O)c1ccc(cc1)N(C)C |r| Show InChI InChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-12,22H,1-4H3,(H,18,20)/b10-5+,13-11+/t12-/m1/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.64E+3	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Miescher Institute for Biomedical Research					Assay Description . Enzymatic characterization (Km determinations, Supplementary Fig. 3C) of zebrafish HDAC6 proteins (CD1-CD2; CD1H193A-CD2; CD1CD2H574A; CD1H193A- CD...				Nat Chem Biol 12: 748-54 (2016) Article DOI: 10.1038/nchembio.2140 BindingDB Entry DOI: 10.7270/Q2V986V6
					More data for this Ligand-Target Pair
Histone deacetylase 5 (Homo sapiens (Human))	BDBM197336 (R-TSA) Show SMILES C[C@H](\C=C\C(=O)NO)\C=C(/C)C(=O)c1ccc(cc1)N(C)C |r| Show InChI InChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-12,22H,1-4H3,(H,18,20)/b10-5+,13-11+/t12-/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.39E+3	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Miescher Institute for Biomedical Research					Assay Description . Enzymatic characterization (Km determinations, Supplementary Fig. 3C) of zebrafish HDAC6 proteins (CD1-CD2; CD1H193A-CD2; CD1CD2H574A; CD1H193A- CD...				Nat Chem Biol 12: 748-54 (2016) Article DOI: 10.1038/nchembio.2140 BindingDB Entry DOI: 10.7270/Q2V986V6
					More data for this Ligand-Target Pair
Histone deacetylase 7 (Homo sapiens (Human))	BDBM197336 (R-TSA) Show SMILES C[C@H](\C=C\C(=O)NO)\C=C(/C)C(=O)c1ccc(cc1)N(C)C |r| Show InChI InChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-12,22H,1-4H3,(H,18,20)/b10-5+,13-11+/t12-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Miescher Institute for Biomedical Research					Assay Description . Enzymatic characterization (Km determinations, Supplementary Fig. 3C) of zebrafish HDAC6 proteins (CD1-CD2; CD1H193A-CD2; CD1CD2H574A; CD1H193A- CD...				Nat Chem Biol 12: 748-54 (2016) Article DOI: 10.1038/nchembio.2140 BindingDB Entry DOI: 10.7270/Q2V986V6
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM197336 (R-TSA) Show SMILES C[C@H](\C=C\C(=O)NO)\C=C(/C)C(=O)c1ccc(cc1)N(C)C |r| Show InChI InChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-12,22H,1-4H3,(H,18,20)/b10-5+,13-11+/t12-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	411	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Miescher Institute for Biomedical Research					Assay Description . Enzymatic characterization (Km determinations, Supplementary Fig. 3C) of zebrafish HDAC6 proteins (CD1-CD2; CD1H193A-CD2; CD1CD2H574A; CD1H193A- CD...				Nat Chem Biol 12: 748-54 (2016) Article DOI: 10.1038/nchembio.2140 BindingDB Entry DOI: 10.7270/Q2V986V6
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM197336 (R-TSA) Show SMILES C[C@H](\C=C\C(=O)NO)\C=C(/C)C(=O)c1ccc(cc1)N(C)C |r| Show InChI InChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-12,22H,1-4H3,(H,18,20)/b10-5+,13-11+/t12-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.86E+3	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Miescher Institute for Biomedical Research					Assay Description . Enzymatic characterization (Km determinations, Supplementary Fig. 3C) of zebrafish HDAC6 proteins (CD1-CD2; CD1H193A-CD2; CD1CD2H574A; CD1H193A- CD...				Nat Chem Biol 12: 748-54 (2016) Article DOI: 10.1038/nchembio.2140 BindingDB Entry DOI: 10.7270/Q2V986V6
					More data for this Ligand-Target Pair
Histone deacetylase 10 (Homo sapiens (Human))	BDBM197336 (R-TSA) Show SMILES C[C@H](\C=C\C(=O)NO)\C=C(/C)C(=O)c1ccc(cc1)N(C)C |r| Show InChI InChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-12,22H,1-4H3,(H,18,20)/b10-5+,13-11+/t12-/m1/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	29.2	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Miescher Institute for Biomedical Research					Assay Description . Enzymatic characterization (Km determinations, Supplementary Fig. 3C) of zebrafish HDAC6 proteins (CD1-CD2; CD1H193A-CD2; CD1CD2H574A; CD1H193A- CD...				Nat Chem Biol 12: 748-54 (2016) Article DOI: 10.1038/nchembio.2140 BindingDB Entry DOI: 10.7270/Q2V986V6
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM197336 (R-TSA) Show SMILES C[C@H](\C=C\C(=O)NO)\C=C(/C)C(=O)c1ccc(cc1)N(C)C |r| Show InChI InChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-12,22H,1-4H3,(H,18,20)/b10-5+,13-11+/t12-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.61E+3	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Miescher Institute for Biomedical Research					Assay Description . Enzymatic characterization (Km determinations, Supplementary Fig. 3C) of zebrafish HDAC6 proteins (CD1-CD2; CD1H193A-CD2; CD1CD2H574A; CD1H193A- CD...				Nat Chem Biol 12: 748-54 (2016) Article DOI: 10.1038/nchembio.2140 BindingDB Entry DOI: 10.7270/Q2V986V6
					More data for this Ligand-Target Pair