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SMILES: N[C@@H]1[C@@H](CC[C@@H](NC(=O)c2cnc3C[C@]4(Cc3c2)C(=O)Nc2ncccc42)c2ncccc12)c1cccc(F)c1F

InChI Key: InChIKey=ZSBONGNUPRAUCB-RGTFHASESA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 200559   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Calcitonin gene-related peptide type 1 receptor


(Homo sapiens (Human))		BDBM200559
PNG
(US9227973, 3)
Show SMILES N[C@@H]1[C@@H](CC[C@@H](NC(=O)c2cnc3C[C@]4(Cc3c2)C(=O)Nc2ncccc42)c2ncccc12)c1cccc(F)c1F |r|
Show InChI InChI=1S/C31H26F2N6O2/c32-22-7-1-4-18(25(22)33)19-8-9-23(27-20(26(19)34)5-2-10-35-27)38-29(40)17-12-16-13-31(14-24(16)37-15-17)21-6-3-11-36-28(21)39-30(31)41/h1-7,10-12,15,19,23,26H,8-9,13-14,34H2,(H,38,40)(H,36,39,41)/t19-,23+,26+,31-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 6.30n/an/an/an/an/a37



Merck Sharp & Dohme Corp.

US Patent


Assay Description
RECOMBINANT RECEPTOR FUNCTIONAL ASSAY (Assay B): Cells were resuspended in DMEM/F12 (Hyclone) supplemented with 1 g/L BSA and 300 μM isobutyl-me...

US Patent US9227973 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7N9K
More data for this
Ligand-Target Pair