BDBM202412 US9238644, 19

SMILES: NC(=O)C1(CC1)c1ccccc1CCc1nc(Nc2cn[nH]c2)ncc1Cl

InChI Key: InChIKey=IDBAAYPNWLPEBC-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 202412   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM202412 (US9238644, 19) Show SMILES NC(=O)C1(CC1)c1ccccc1CCc1nc(Nc2cn[nH]c2)ncc1Cl Show InChI InChI=1S/C19H19ClN6O/c20-15-11-22-18(25-13-9-23-24-10-13)26-16(15)6-5-12-3-1-2-4-14(12)19(7-8-19)17(21)27/h1-4,9-11H,5-8H2,(H2,21,27)(H,23,24)(H,22,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	248	n/a	n/a	n/a	n/a	7.2	37
CANCER THERAPEUTICS CRC PTY LIMITED US Patent					Assay Description Adult human umbilical vein endothelial cells (HUVEC) (Cat# CC-2519, Lonza) were seeded into clear-bottom, TC treated 12 well plates (Cat #665180, G...				US Patent US9238644 (2016) BindingDB Entry DOI: 10.7270/Q2JM28FP
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 3 (Homo sapiens (Human))	BDBM202412 (US9238644, 19) Show SMILES NC(=O)C1(CC1)c1ccccc1CCc1nc(Nc2cn[nH]c2)ncc1Cl Show InChI InChI=1S/C19H19ClN6O/c20-15-11-22-18(25-13-9-23-24-10-13)26-16(15)6-5-12-3-1-2-4-14(12)19(7-8-19)17(21)27/h1-4,9-11H,5-8H2,(H2,21,27)(H,23,24)(H,22,25,26)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	7.2	37
CANCER THERAPEUTICS CRC PTY LIMITED US Patent					Assay Description Adult human dermal lymphatic microvascular endothelial cells (HMVEC-dLyAD) (Cat# CC-2810, Lonza) were seeded into clear-bottom, TC treated 12 well pl...				US Patent US9238644 (2016) BindingDB Entry DOI: 10.7270/Q2JM28FP
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 3 (Homo sapiens (Human))	BDBM202412 (US9238644, 19) Show SMILES NC(=O)C1(CC1)c1ccccc1CCc1nc(Nc2cn[nH]c2)ncc1Cl Show InChI InChI=1S/C19H19ClN6O/c20-15-11-22-18(25-13-9-23-24-10-13)26-16(15)6-5-12-3-1-2-4-14(12)19(7-8-19)17(21)27/h1-4,9-11H,5-8H2,(H2,21,27)(H,23,24)(H,22,25,26)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.4	n/a
CANCER THERAPEUTICS CRC PTY LIMITED US Patent					Assay Description A biotin labelled peptide is used as substrate (amino acid sequence: Biotin-Glu-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH2)....				US Patent US9238644 (2016) BindingDB Entry DOI: 10.7270/Q2JM28FP
					More data for this Ligand-Target Pair