null
SMILES: CCOC(=O)c1cccc(NC(=O)N2CCC(CC2)N2CCc3ccc(F)cc23)c1
InChI Key: InChIKey=OROSDPGIEXRTFT-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Acyl-CoA desaturase 1 (Rattus norvegicus (Rat)) | BDBM202517 (US9238658, 41) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 534 | n/a | n/a | n/a | n/a | n/a | 25 |
Janssen Pharmaceutica NV US Patent | Assay Description The SCD1 enzymatic assay was done in a volume of 50 uL using 10 ug of RLM (prepared as described above) in a 96-well polypropylene plate (enzyme reac... | US Patent US9238658 (2016) BindingDB Entry DOI: 10.7270/Q2930S1D | |||||||||||
More data for this Ligand-Target Pair |