BDBM20302 2-[(3,4-dimethylphenyl)methyl]-3-{[1-(4-methanesulfonamidophenyl)cyclopropyl]formamido}propyl 2,2-dimethylpropanoate::cyclopropyl amide analogue, 26

SMILES: Cc1ccc(CC(CNC(=O)C2(CC2)c2ccc(NS(C)(=O)=O)cc2)COC(=O)C(C)(C)C)cc1C

InChI Key: InChIKey=CXTIQQLCXJJMIN-UHFFFAOYSA-N

Data: 1 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 20302   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vanilloid receptor (Rattus norvegicus (rat))	BDBM20302 (2-[(3,4-dimethylphenyl)methyl]-3-{[1-(4-methanesul...) Show SMILES Cc1ccc(CC(CNC(=O)C2(CC2)c2ccc(NS(C)(=O)=O)cc2)COC(=O)C(C)(C)C)cc1C Show InChI InChI=1S/C28H38N2O5S/c1-19-7-8-21(15-20(19)2)16-22(18-35-26(32)27(3,4)5)17-29-25(31)28(13-14-28)23-9-11-24(12-10-23)30-36(6,33)34/h7-12,15,22,30H,13-14,16-18H2,1-6H3,(H,29,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	396	-9.08	n/a	n/a	197	n/a	n/a	7.4	37
Seoul National University					Assay Description Binding assay mixtures were set up and contained [3H] RTX, various concentrations of competing ligands, and rVR1-transfected CHO cells. Nonspecific b...				J Med Chem 51: 57-67 (2008) Article DOI: 10.1021/jm701049p BindingDB Entry DOI: 10.7270/Q2222S1N
					More data for this Ligand-Target Pair