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SMILES: O=C(NC(CC#N)c1ccccc1)Nc1cccc2cnccc12

InChI Key: InChIKey=GVBMRMLFGASFRA-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 20397   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))		BDBM20397
PNG
(3-(2-cyano-1-phenylethyl)-1-isoquinolin-5-ylurea |...)
Show SMILES O=C(NC(CC#N)c1ccccc1)Nc1cccc2cnccc12
Show InChI InChI=1S/C19H16N4O/c20-11-9-17(14-5-2-1-3-6-14)22-19(24)23-18-8-4-7-15-13-21-12-10-16(15)18/h1-8,10,12-13,17H,9H2,(H2,22,23,24)
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Article
PubMed
n/an/an/an/a 1.59E+4n/an/a7.422



Abbott Laboratories



Assay Description
The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...

Bioorg Med Chem Lett 17: 3894-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.04.105
BindingDB Entry DOI: 10.7270/Q2NV9GH2
More data for this
Ligand-Target Pair