BDBM20448 3-1H-indazol-4-yl-1-{[4-(trifluoromethyl)phenyl]methyl}urea::heterocyclic urea, 47

SMILES: FC(F)(F)c1ccc(CNC(=O)Nc2cccc3[nH]ncc23)cc1

InChI Key: InChIKey=MMDHAGYNJNCDAF-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 20448   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM20448 (3-1H-indazol-4-yl-1-{[4-(trifluoromethyl)phenyl]me...) Show SMILES FC(F)(F)c1ccc(CNC(=O)Nc2cccc3[nH]ncc23)cc1 Show InChI InChI=1S/C16H13F3N4O/c17-16(18,19)11-6-4-10(5-7-11)8-20-15(24)22-13-2-1-3-14-12(13)9-21-23-14/h1-7,9H,8H2,(H,21,23)(H2,20,22,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	9	n/a	n/a	7.4	22
Abbott Laboratories					Assay Description The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...				Bioorg Med Chem 14: 4740-9 (2006) Article DOI: 10.1016/j.bmc.2006.03.027 BindingDB Entry DOI: 10.7270/Q2DB8035
					More data for this Ligand-Target Pair