BDBM204627 1-(5-butoxy-2-chloro-phenyl)-4-methyl-[1,2,4]triazolo[4,3-a]quinoxaline::US9540379, 41

SMILES: CCCCOc1ccc(Cl)c(c1)-c1nnc2c(C)nc3ccccc3n12

InChI Key: InChIKey=ITEIGISUTJIFPA-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 204627   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Homo sapiens phosphodiesterase 2A (PDE2A) (Homo sapiens (Human))	BDBM204627 (1-(5-butoxy-2-chloro-phenyl)-4-methyl-[1,2,4]triaz...) Show SMILES CCCCOc1ccc(Cl)c(c1)-c1nnc2c(C)nc3ccccc3n12 Show InChI InChI=1S/C20H19ClN4O/c1-3-4-11-26-14-9-10-16(21)15(12-14)20-24-23-19-13(2)22-17-7-5-6-8-18(17)25(19)20/h5-10,12H,3-4,11H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The DNA encoding PDE2A (NM002599) was cloned and the gene was inserted in the baculovirus and the enzyme-protein expressed in SF21-cells. The enzyme ...				US Patent US9540379 (2017) BindingDB Entry DOI: 10.7270/Q2RB72SP
					More data for this Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM204627 (1-(5-butoxy-2-chloro-phenyl)-4-methyl-[1,2,4]triaz...) Show SMILES CCCCOc1ccc(Cl)c(c1)-c1nnc2c(C)nc3ccccc3n12 Show InChI InChI=1S/C20H19ClN4O/c1-3-4-11-26-14-9-10-16(21)15(12-14)20-24-23-19-13(2)22-17-7-5-6-8-18(17)25(19)20/h5-10,12H,3-4,11H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The DNA of PDE10A1 (AB 020593, 2340 bp) was synthesized and cloned into the vector pCR4. TOPO (Entelechon GmbH, Regensburg, Germany). The gene was th...				US Patent US9540379 (2017) BindingDB Entry DOI: 10.7270/Q2RB72SP
					More data for this Ligand-Target Pair