BDBM208049 3-((3,5-Dichlorophenyl)thio)-6-ethyl-1H-indole-2-carboxylic acid ::US9233921, 25

SMILES: CCc1ccc2c(Sc3cc(Cl)cc(Cl)c3)c([nH]c2c1)C(O)=O

InChI Key: InChIKey=JJMDJVIEEWWBMB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 208049   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Uracil-DNA glycosylase (Vaccinia virus (strain Copenhagen) (VACV))	BDBM208049 (3-((3,5-Dichlorophenyl)thio)-6-ethyl-1H-indole-2-c...) Show SMILES CCc1ccc2c(Sc3cc(Cl)cc(Cl)c3)c([nH]c2c1)C(O)=O Show InChI InChI=1S/C17H13Cl2NO2S/c1-2-9-3-4-13-14(5-9)20-15(17(21)22)16(13)23-12-7-10(18)6-11(19)8-12/h3-8,20H,2H2,1H3,(H,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	37
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA US Patent					Assay Description African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...				US Patent US9233921 (2016) BindingDB Entry DOI: 10.7270/Q2222SM8
					More data for this Ligand-Target Pair