BDBM209276 US9266883, 34

SMILES: O=Cc1ccc2CCCN(C(=O)Nc3cc(OCC4CCCO4)c(cn3)C#N)c2n1

InChI Key: InChIKey=JLGPVFMSMFEQTJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 209276   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 4 [388-802] (Homo sapiens (Human))	BDBM209276 (US9266883, 34) Show SMILES O=Cc1ccc2CCCN(C(=O)Nc3cc(OCC4CCCO4)c(cn3)C#N)c2n1 Show InChI InChI=1S/C21H21N5O4/c22-10-15-11-23-19(9-18(15)30-13-17-4-2-8-29-17)25-21(28)26-7-1-3-14-5-6-16(12-27)24-20(14)26/h5-6,9,11-12,17H,1-4,7-8,13H2,(H,23,25,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10	n/a	n/a	n/a	n/a	7.5	30
Novartis AG US Patent					Assay Description Liquid handling and incubation steps were done on an Innovadyne Nanodrop Express equipped with a robotic arm (Thermo CatX, Caliper Twister II) and an...				US Patent US9266883 (2016) BindingDB Entry DOI: 10.7270/Q2CC0ZGP
					More data for this Ligand-Target Pair