BDBM209895 US9273014, 24
SMILES: NC(=O)[C@@H](CCC(F)(F)F)[C@@H](CCC(F)(F)F)C(=O)N[C@H]1N=C(c2ccccc2)c2cccc(C3CC3)c2NC1=O
InChI Key: InChIKey=UGHSMELYSLKUPL-XLNZFTOWSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Notch 3 intracellular domain (Notch 3) (Homo sapiens (Human)) | BDBM209895 (US9273014, 24) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays. | US Patent US9273014 (2016) BindingDB Entry DOI: 10.7270/Q2KW5DVX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Notch 1 intracellular domain (Notch 1) (Homo sapiens (Human)) | BDBM209895 (US9273014, 24) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description The pharmacological properties of the compounds of this invention may be confirmed by a number of biological assays. | US Patent US9273014 (2016) BindingDB Entry DOI: 10.7270/Q2KW5DVX | |||||||||||
More data for this Ligand-Target Pair |