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SMILES: Cc1nc2c(OCc3c(F)cccc3F)cccn2c1C(=O)NC(CO)(CO)c1ccc(F)cc1

InChI Key: InChIKey=CZUGKPRHQSNSDY-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 213295   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Guanylate cyclase soluble subunit alpha-1/beta-1


(Homo sapiens (Human))		BDBM213295
PNG
(US9278968, 54)
Show SMILES Cc1nc2c(OCc3c(F)cccc3F)cccn2c1C(=O)NC(CO)(CO)c1ccc(F)cc1
Show InChI InChI=1S/C25H22F3N3O4/c1-15-22(24(34)30-25(13-32,14-33)16-7-9-17(26)10-8-16)31-11-3-6-21(23(31)29-15)35-12-18-19(27)4-2-5-20(18)28/h2-11,32-33H,12-14H2,1H3,(H,30,34)
PDB
MMDB

UniProtKB/SwissProt

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antibodypedia
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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 2.70E+3n/an/an/a25



Astellas Pharma Inc.

US Patent


Assay Description
Using an sGCα 1 gene (NCBI accession No. BC028384.2) and an sGCβ1 gene (NCBI accession No. BC047620.1), an N-terminal FLAG tag-fused sGC&a...

US Patent US9278968 (2016)


BindingDB Entry DOI: 10.7270/Q2T43RXS
More data for this
Ligand-Target Pair