BDBM218250 US9260435, 8

SMILES: COc1nc(cn2c(c(nc12)-c1ccc(cc1)C1(N)CCC1)-c1ccccc1)C(N)=O

InChI Key: InChIKey=QATMYBCFWXFYLG-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 218250   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase AKT2 (Homo sapiens (Human))	BDBM218250 (US9260435, 8) Show SMILES COc1nc(cn2c(c(nc12)-c1ccc(cc1)C1(N)CCC1)-c1ccccc1)C(N)=O Show InChI InChI=1S/C24H23N5O2/c1-31-23-22-28-19(15-8-10-17(11-9-15)24(26)12-5-13-24)20(16-6-3-2-4-7-16)29(22)14-18(27-23)21(25)30/h2-4,6-11,14H,5,12-13,26H2,1H3,(H2,25,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	7.5	22
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description His-tagged human recombinant kinase full-length Akt2 expressed in insect cells and activated by PDK1 was purchased from Invitrogen (part number PV 39...				US Patent US9260435 (2016) BindingDB Entry DOI: 10.7270/Q2K936CJ
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM218250 (US9260435, 8) Show SMILES COc1nc(cn2c(c(nc12)-c1ccc(cc1)C1(N)CCC1)-c1ccccc1)C(N)=O Show InChI InChI=1S/C24H23N5O2/c1-31-23-22-28-19(15-8-10-17(11-9-15)24(26)12-5-13-24)20(16-6-3-2-4-7-16)29(22)14-18(27-23)21(25)30/h2-4,6-11,14H,5,12-13,26H2,1H3,(H2,25,30)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	29	n/a	n/a	n/a	n/a	7.5	22
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description His-tagged human recombinant kinase full-length Akt1 expressed in insect cells was purchased form Invitrogen (part number PV 3599). As substrate for ...				US Patent US9260435 (2016) BindingDB Entry DOI: 10.7270/Q2K936CJ
					More data for this Ligand-Target Pair