null

SMILES: FC(F)(F)c1cccc(Nc2cc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1

InChI Key: InChIKey=IUUVGECHVYLVCB-NSIKDUERSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 218852   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Casein kinase II subunit alpha/beta (Homo sapiens (Human)-Rattus norvegicus)	BDBM218852 (US9303033, J1, Table 4A, Compound 4 | US9303033, Z...) Show SMILES FC(F)(F)c1cccc(Nc2cc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 Show InChI InChI=1S/C20H16F3N7O2/c21-20(22,23)11-2-1-3-13(7-11)25-15-8-16(26-12-4-5-12)30-17(28-15)10(9-24-30)6-14-18(31)29-19(32)27-14/h1-3,6-9,12,26H,4-5H2,(H,25,28)(H2,27,29,31,32)/b14-6-	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	7.2	n/a
SENHWA BIOSCIENCES, INC. US Patent					Assay Description In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...				US Patent US9303033 (2016) BindingDB Entry DOI: 10.7270/Q2CN72RX
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha/beta (Homo sapiens (Human)-Rattus norvegicus)	BDBM218852 (US9303033, J1, Table 4A, Compound 4 | US9303033, Z...) Show SMILES FC(F)(F)c1cccc(Nc2cc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 Show InChI InChI=1S/C20H16F3N7O2/c21-20(22,23)11-2-1-3-13(7-11)25-15-8-16(26-12-4-5-12)30-17(28-15)10(9-24-30)6-14-18(31)29-19(32)27-14/h1-3,6-9,12,26H,4-5H2,(H,25,28)(H2,27,29,31,32)/b14-6-	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	7.2	n/a
SENHWA BIOSCIENCES, INC. US Patent					Assay Description In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...				US Patent US9303033 (2016) BindingDB Entry DOI: 10.7270/Q2CN72RX
					More data for this Ligand-Target Pair
Casein kinase II subunit beta (Homo sapiens (Human))	BDBM218852 (US9303033, J1, Table 4A, Compound 4 | US9303033, Z...) Show SMILES FC(F)(F)c1cccc(Nc2cc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 Show InChI InChI=1S/C20H16F3N7O2/c21-20(22,23)11-2-1-3-13(7-11)25-15-8-16(26-12-4-5-12)30-17(28-15)10(9-24-30)6-14-18(31)29-19(32)27-14/h1-3,6-9,12,26H,4-5H2,(H,25,28)(H2,27,29,31,32)/b14-6-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.48E+3	n/a	n/a	n/a	n/a	7.0	n/a
SENHWA BIOSCIENCES, INC. US Patent					Assay Description 5 uM ATP: Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5× Reaction Buffer (40 m...				US Patent US9303033 (2016) BindingDB Entry DOI: 10.7270/Q2CN72RX
					More data for this Ligand-Target Pair