BDBM218929 US9303033, J4, Table 13A, Compound 18::US9303033, Q7, Table 22A, Compound 11

SMILES: CN(C)c1ccc(cc1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1

InChI Key: InChIKey=UXBZGXCXOAYKLC-MFOYZWKCSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 218929   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Casein kinase II alpha/beta (Homo sapiens (Human)-Rattus norvegicus)	BDBM218929 (US9303033, J4, Table 13A, Compound 18 | US9303033,...) Show SMILES CN(C)c1ccc(cc1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 Show InChI InChI=1S/C21H21N7O2/c1-27(2)15-7-3-12(4-8-15)16-10-18(23-14-5-6-14)28-19(24-16)13(11-22-28)9-17-20(29)26-21(30)25-17/h3-4,7-11,14,23H,5-6H2,1-2H3,(H2,25,26,29,30)/b17-9-	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	7.2	n/a
SENHWA BIOSCIENCES, INC. US Patent					Assay Description In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...				US Patent US9303033 (2016) BindingDB Entry DOI: 10.7270/Q2CN72RX
					More data for this Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta) (Homo sapiens (Human))	BDBM218929 (US9303033, J4, Table 13A, Compound 18 | US9303033,...) Show SMILES CN(C)c1ccc(cc1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 Show InChI InChI=1S/C21H21N7O2/c1-27(2)15-7-3-12(4-8-15)16-10-18(23-14-5-6-14)28-19(24-16)13(11-22-28)9-17-20(29)26-21(30)25-17/h3-4,7-11,14,23H,5-6H2,1-2H3,(H2,25,26,29,30)/b17-9-	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	7.0	n/a
SENHWA BIOSCIENCES, INC. US Patent					Assay Description 5 uM ATP: Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5× Reaction Buffer (40 m...				US Patent US9303033 (2016) BindingDB Entry DOI: 10.7270/Q2CN72RX
					More data for this Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta) (Homo sapiens (Human))	BDBM218929 (US9303033, J4, Table 13A, Compound 18 | US9303033,...) Show SMILES CN(C)c1ccc(cc1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 Show InChI InChI=1S/C21H21N7O2/c1-27(2)15-7-3-12(4-8-15)16-10-18(23-14-5-6-14)28-19(24-16)13(11-22-28)9-17-20(29)26-21(30)25-17/h3-4,7-11,14,23H,5-6H2,1-2H3,(H2,25,26,29,30)/b17-9-	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	867	n/a	n/a	n/a	n/a	7.0	n/a
SENHWA BIOSCIENCES, INC. US Patent					Assay Description 5 uM ATP: Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5× Reaction Buffer (40 m...				US Patent US9303033 (2016) BindingDB Entry DOI: 10.7270/Q2CN72RX
					More data for this Ligand-Target Pair
Casein kinase II alpha/beta (Homo sapiens (Human)-Rattus norvegicus)	BDBM218929 (US9303033, J4, Table 13A, Compound 18 | US9303033,...) Show SMILES CN(C)c1ccc(cc1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 Show InChI InChI=1S/C21H21N7O2/c1-27(2)15-7-3-12(4-8-15)16-10-18(23-14-5-6-14)28-19(24-16)13(11-22-28)9-17-20(29)26-21(30)25-17/h3-4,7-11,14,23H,5-6H2,1-2H3,(H2,25,26,29,30)/b17-9-	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.2	n/a
SENHWA BIOSCIENCES, INC. US Patent					Assay Description In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...				US Patent US9303033 (2016) BindingDB Entry DOI: 10.7270/Q2CN72RX
					More data for this Ligand-Target Pair