null

SMILES: C[C@H](Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=VWAAMJVETWDLFF-SOOGHKCXSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 219435   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Casein kinase II subunit beta (Homo sapiens (Human))	BDBM219435 (US9303033, F24, Table 37A, Compound 109) Show SMILES C[C@H](Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccc(cc1)C(F)(F)F |r| Show InChI InChI=1S/C21H19F3N8O2/c1-10(11-2-4-13(5-3-11)21(22,23)24)26-18-29-16-12(8-15-17(33)30-20(34)28-15)9-25-32(16)19(31-18)27-14-6-7-14/h2-5,8-10,14H,6-7H2,1H3,(H2,26,27,29,31)(H2,28,30,33,34)/b15-8-/t10-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	314	n/a	n/a	n/a	n/a	7.0	n/a
SENHWA BIOSCIENCES, INC. US Patent					Assay Description Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5× Reaction Buffer (40 mM MOPS pH ...				US Patent US9303033 (2016) BindingDB Entry DOI: 10.7270/Q2CN72RX
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha/beta (Homo sapiens (Human)-Rattus norvegicus)	BDBM219435 (US9303033, F24, Table 37A, Compound 109) Show SMILES C[C@H](Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccc(cc1)C(F)(F)F |r| Show InChI InChI=1S/C21H19F3N8O2/c1-10(11-2-4-13(5-3-11)21(22,23)24)26-18-29-16-12(8-15-17(33)30-20(34)28-15)9-25-32(16)19(31-18)27-14-6-7-14/h2-5,8-10,14H,6-7H2,1H3,(H2,26,27,29,31)(H2,28,30,33,34)/b15-8-/t10-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.2	n/a
SENHWA BIOSCIENCES, INC. US Patent					Assay Description In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...				US Patent US9303033 (2016) BindingDB Entry DOI: 10.7270/Q2CN72RX
					More data for this Ligand-Target Pair