null

SMILES: Clc1ccc(COc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1

InChI Key: InChIKey=YTWUMEOPIJMKEC-AUWJEWJLSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 220057   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Casein kinase II subunit beta (Homo sapiens (Human))	BDBM220057 (US9303033, A48, Table 58A, Compound 24 | US9303033...) Show SMILES Clc1ccc(COc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1 Show InChI InChI=1S/C19H16ClN7O3/c20-12-3-1-10(2-4-12)9-30-19-24-15-11(7-14-16(28)25-18(29)23-14)8-21-27(15)17(26-19)22-13-5-6-13/h1-4,7-8,13H,5-6,9H2,(H,22,24,26)(H2,23,25,28,29)/b14-7-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.28E+4	n/a	n/a	n/a	n/a	7.0	n/a
SENHWA BIOSCIENCES, INC. US Patent					Assay Description Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5× Reaction Buffer (40 mM MOPS pH ...				US Patent US9303033 (2016) BindingDB Entry DOI: 10.7270/Q2CN72RX
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha/beta (Homo sapiens (Human)-Rattus norvegicus)	BDBM220057 (US9303033, A48, Table 58A, Compound 24 | US9303033...) Show SMILES Clc1ccc(COc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1 Show InChI InChI=1S/C19H16ClN7O3/c20-12-3-1-10(2-4-12)9-30-19-24-15-11(7-14-16(28)25-18(29)23-14)8-21-27(15)17(26-19)22-13-5-6-13/h1-4,7-8,13H,5-6,9H2,(H,22,24,26)(H2,23,25,28,29)/b14-7-	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	7.2	n/a
SENHWA BIOSCIENCES, INC. US Patent					Assay Description In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...				US Patent US9303033 (2016) BindingDB Entry DOI: 10.7270/Q2CN72RX
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha/beta (Homo sapiens (Human)-Rattus norvegicus)	BDBM220057 (US9303033, A48, Table 58A, Compound 24 | US9303033...) Show SMILES Clc1ccc(COc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1 Show InChI InChI=1S/C19H16ClN7O3/c20-12-3-1-10(2-4-12)9-30-19-24-15-11(7-14-16(28)25-18(29)23-14)8-21-27(15)17(26-19)22-13-5-6-13/h1-4,7-8,13H,5-6,9H2,(H,22,24,26)(H2,23,25,28,29)/b14-7-	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	7.2	n/a
SENHWA BIOSCIENCES, INC. US Patent					Assay Description In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...				US Patent US9303033 (2016) BindingDB Entry DOI: 10.7270/Q2CN72RX
					More data for this Ligand-Target Pair
Casein kinase II subunit beta (Homo sapiens (Human))	BDBM220057 (US9303033, A48, Table 58A, Compound 24 | US9303033...) Show SMILES Clc1ccc(COc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1 Show InChI InChI=1S/C19H16ClN7O3/c20-12-3-1-10(2-4-12)9-30-19-24-15-11(7-14-16(28)25-18(29)23-14)8-21-27(15)17(26-19)22-13-5-6-13/h1-4,7-8,13H,5-6,9H2,(H,22,24,26)(H2,23,25,28,29)/b14-7-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.14E+4	n/a	n/a	n/a	n/a	7.0	n/a
SENHWA BIOSCIENCES, INC. US Patent					Assay Description Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5× Reaction Buffer (40 mM MOPS pH ...				US Patent US9303033 (2016) BindingDB Entry DOI: 10.7270/Q2CN72RX
					More data for this Ligand-Target Pair