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SMILES: Cn1nccc1Cc1cnc2n(CC(=O)N3CC(C)(C)C3)c(=O)c(cc2c1)C(=O)NCc1ccc(Cl)cc1

InChI Key: InChIKey=NPLNCYGYEWICEO-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 222909   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
DNA polymerase catalytic subunit


(Human cytomegalovirus (HCMV strain AD169) )		BDBM222909
PNG
(US9315499, 4020)
Show SMILES Cn1nccc1Cc1cnc2n(CC(=O)N3CC(C)(C)C3)c(=O)c(cc2c1)C(=O)NCc1ccc(Cl)cc1
Show InChI InChI=1S/C28H29ClN6O3/c1-28(2)16-34(17-28)24(36)15-35-25-20(10-19(14-30-25)11-22-8-9-32-33(22)3)12-23(27(35)38)26(37)31-13-18-4-6-21(29)7-5-18/h4-10,12,14H,11,13,15-17H2,1-3H3,(H,31,37)
UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 65n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
The assay conditions are the following: 10 mM HEPES pH 7.5, 25 mM KCl, 7.5 mM NaCl, 5 mM MgCl2, 0.2 mg BSA/mL, 1 mM TCEP, 1.5% glycerol, 5% DMSO, 235...

US Patent US9315499 (2016)


BindingDB Entry DOI: 10.7270/Q2028QCZ
More data for this
Ligand-Target Pair