BDBM223980 6,7-Dichloro-N-cyclopentylquinolin-4-amine (2)

SMILES: Clc1cc2nccc(NC3CCCC3)c2cc1Cl

InChI Key: InChIKey=CMPRHICRGYUFAI-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 223980   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein lysine methyltransferase SUV4-20H2 (SUV4-20H2) (Homo sapiens (Human))	BDBM223980 (6,7-Dichloro-N-cyclopentylquinolin-4-amine (2)) Show SMILES Clc1cc2nccc(NC3CCCC3)c2cc1Cl Show InChI InChI=1S/C14H14Cl2N2/c15-11-7-10-13(18-9-3-1-2-4-9)5-6-17-14(10)8-12(11)16/h5-9H,1-4H2,(H,17,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	8.0	25
AbbVie					Assay Description Experiments were performed in triplicate at room temperature with 1 h incubation of 10 μl reaction mixture in buffer of 20 mM Tris-HCl, pH 8.0, ...				Nat Chem Biol 13: 317-324 (2017) Article DOI: 10.1038/nchembio.2282 BindingDB Entry DOI: 10.7270/Q2X065XF
					More data for this Ligand-Target Pair
Protein lysine methyltransferase SUV4-20H1 (SUV4-20H1) (Homo sapiens (Human))	BDBM223980 (6,7-Dichloro-N-cyclopentylquinolin-4-amine (2)) Show SMILES Clc1cc2nccc(NC3CCCC3)c2cc1Cl Show InChI InChI=1S/C14H14Cl2N2/c15-11-7-10-13(18-9-3-1-2-4-9)5-6-17-14(10)8-12(11)16/h5-9H,1-4H2,(H,17,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	590	n/a	n/a	n/a	n/a	8.0	25
AbbVie					Assay Description Experiments were performed in triplicate at room temperature with 1 h incubation of 10 μl reaction mixture in buffer of 20 mM Tris-HCl, pH 8.0, ...				Nat Chem Biol 13: 317-324 (2017) Article DOI: 10.1038/nchembio.2282 BindingDB Entry DOI: 10.7270/Q2X065XF
					More data for this Ligand-Target Pair