BDBM224602 US10202383, Example 2(151)::US9321791, 2(151)::US9556175, 2(151)

SMILES: CC#CCn1c(nc2n(C)c(=O)n(CC(=O)c3ccccc3NC(=O)C(C)C)c(=O)c12)N1CCC[C@@H](N)C1

InChI Key: InChIKey=RSDDHYXHNHAYEN-GOSISDBHSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 224602   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM224602 (US10202383, Example 2(151) | US9321791, 2(151) | U...) Show SMILES CC#CCn1c(nc2n(C)c(=O)n(CC(=O)c3ccccc3NC(=O)C(C)C)c(=O)c12)N1CCC[C@@H](N)C1 Show InChI InChI=1S/C27H33N7O4/c1-5-6-14-33-22-23(30-26(33)32-13-9-10-18(28)15-32)31(4)27(38)34(25(22)37)16-21(35)19-11-7-8-12-20(19)29-24(36)17(2)3/h7-8,11-12,17-18H,9-10,13-16,28H2,1-4H3,(H,29,36)/t18-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.8	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description 50 μl substrate solution (AFC; AFC is amido-4-trifluoromethylcoumarin), final concentration 100 μM, were placed in black microtitre plates. 20 ...				US Patent US9321791 (2016) BindingDB Entry DOI: 10.7270/Q2GQ6WNR
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM224602 (US10202383, Example 2(151) | US9321791, 2(151) | U...) Show SMILES CC#CCn1c(nc2n(C)c(=O)n(CC(=O)c3ccccc3NC(=O)C(C)C)c(=O)c12)N1CCC[C@@H](N)C1 Show InChI InChI=1S/C27H33N7O4/c1-5-6-14-33-22-23(30-26(33)32-13-9-10-18(28)15-32)31(4)27(38)34(25(22)37)16-21(35)19-11-7-8-12-20(19)29-24(36)17(2)3/h7-8,11-12,17-18H,9-10,13-16,28H2,1-4H3,(H,29,36)/t18-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description 50 μl substrate solution (AFC; AFC is amido-4-trifluoromethylcoumarin), final concentration 100 μM, were placed in black microtitre plates....				US Patent US10202383 (2019) BindingDB Entry DOI: 10.7270/Q2P55QNN
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM224602 (US10202383, Example 2(151) | US9321791, 2(151) | U...) Show SMILES CC#CCn1c(nc2n(C)c(=O)n(CC(=O)c3ccccc3NC(=O)C(C)C)c(=O)c12)N1CCC[C@@H](N)C1 Show InChI InChI=1S/C27H33N7O4/c1-5-6-14-33-22-23(30-26(33)32-13-9-10-18(28)15-32)31(4)27(38)34(25(22)37)16-21(35)19-11-7-8-12-20(19)29-24(36)17(2)3/h7-8,11-12,17-18H,9-10,13-16,28H2,1-4H3,(H,29,36)/t18-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.8	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description 50 μl substrate solution (AFC; AFC is amido-4-trifluoromethylcoumarin), final concentration 100 μM, were placed in black microtitre plates....				US Patent US9556175 (2017) BindingDB Entry DOI: 10.7270/Q2Z03B5T
					More data for this Ligand-Target Pair