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BDBM22535 4-Benzyl-1H-imidazole derivative, 16::4-[3-(1H-imidazol-4-ylmethyl)phenyl]pyridine

SMILES: C(c1cnc[nH]1)c1cccc(c1)-c1ccncc1

InChI Key: InChIKey=IIPGNQAIZQFUPT-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 22535   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM22535
PNG
(4-Benzyl-1H-imidazole derivative, 16 | 4-[3-(1H-im...)
Show SMILES C(c1cnc[nH]1)c1cccc(c1)-c1ccncc1
Show InChI InChI=1S/C15H13N3/c1-2-12(9-15-10-17-11-18-15)8-14(3-1)13-4-6-16-7-5-13/h1-8,10-11H,9H2,(H,17,18)
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UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
427 -8.68n/an/an/an/an/a7.425



VU University Amsterdam



Assay Description
Ligand displacement assays were performed on CHO cells membranes expressing hH3R. Retained radioactivity was determined by liquid scintillation count...


J Med Chem 51: 2944-53 (2008)


Article DOI: 10.1021/jm7014149
BindingDB Entry DOI: 10.7270/Q24F1P2W
More data for this
Ligand-Target Pair