BDBM2261 2-Pyridinone derivative 41::3-[(1,3-benzoxazol-2-ylamino)methyl]-5-ethyl-6-methyl-1,2-dihydropyridin-2-one::3-{[(Benzoxazol-2-yl)amino]methyl}-5-ethyl-6-methylpyridin-2(1H)-one::CHEMBL175089

SMILES: CCc1cc(CNc2nc3ccccc3o2)c(=O)[nH]c1C

InChI Key: InChIKey=JOJRZHBMXFTUHG-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 2261   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM2261 (2-Pyridinone derivative 41 | 3-[(1,3-benzoxazol-2-...) Show SMILES CCc1cc(CNc2nc3ccccc3o2)c(=O)[nH]c1C Show InChI InChI=1S/C16H17N3O2/c1-3-11-8-12(15(20)18-10(11)2)9-17-16-19-13-6-4-5-7-14(13)21-16/h4-8H,3,9H2,1-2H3,(H,17,19)(H,18,20)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	1.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Reserch Laboratories Curated by ChEMBL					Assay Description Tested for inhibition against HIV-1 RT (used (poly)rC-(oligo)dG as the template)				J Med Chem 36: 953-66 (1993) BindingDB Entry DOI: 10.7270/Q2JW8G28
					More data for this Ligand-Target Pair
HIV-1 Reverse Transcriptase (Human immunodeficiency virus type 1)	BDBM2261 (2-Pyridinone derivative 41 | 3-[(1,3-benzoxazol-2-...) Show SMILES CCc1cc(CNc2nc3ccccc3o2)c(=O)[nH]c1C Show InChI InChI=1S/C16H17N3O2/c1-3-11-8-12(15(20)18-10(11)2)9-17-16-19-13-6-4-5-7-14(13)21-16/h4-8H,3,9H2,1-2H3,(H,17,19)(H,18,20)	PDB MMDB B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	1.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Reserch Laboratories Curated by ChEMBL					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 36: 953-66 (1993) BindingDB Entry DOI: 10.7270/Q2JW8G28
					More data for this Ligand-Target Pair