Found 3 hits for monomerid = 22917 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Adenosine deaminase
(Homo sapiens (Human)) | BDBM22917
(1-(1-hydroxy-4-phenylbutan-2-yl)-1H-imidazole-4-ca...)Show InChI InChI=1S/C14H17N3O2/c15-14(19)13-8-17(10-16-13)12(9-18)7-6-11-4-2-1-3-5-11/h1-5,8,10,12,18H,6-7,9H2,(H2,15,19) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| 5.90E+3 | -7.06 | n/a | n/a | n/a | n/a | n/a | 7.4 | 22 |
Fujisawa Pharmaceutical Co., Ltd.
| Assay Description The reaction velocity was measured by change in absorbance at 265nm (A265) resulting from the deamination of adenosine. The reaction was started by a... |
J Am Chem Soc 126: 34-5 (2004)
Article DOI: 10.1021/ja038606l BindingDB Entry DOI: 10.7270/Q2FQ9TWW |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Adenosine deaminase
(Homo sapiens (Human)) | BDBM22917
(1-(1-hydroxy-4-phenylbutan-2-yl)-1H-imidazole-4-ca...)Show InChI InChI=1S/C14H17N3O2/c15-14(19)13-8-17(10-16-13)12(9-18)7-6-11-4-2-1-3-5-11/h1-5,8,10,12,18H,6-7,9H2,(H2,15,19) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| 5.90E+3 | -7.06 | n/a | n/a | n/a | n/a | n/a | 7.4 | 22 |
Fujisawa Pharmaceutical Co., Ltd.
| Assay Description The reaction velocity was measured by change in absorbance at 265nm (A265) resulting from the deamination of adenosine. The reaction was started by a... |
Bioorg Med Chem Lett 13: 1115-8 (2003)
Article DOI: 10.1016/S0960-894X(03)00026-X BindingDB Entry DOI: 10.7270/Q29Z936D |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Adenosine deaminase
(Homo sapiens (Human)) | BDBM22917
(1-(1-hydroxy-4-phenylbutan-2-yl)-1H-imidazole-4-ca...)Show InChI InChI=1S/C14H17N3O2/c15-14(19)13-8-17(10-16-13)12(9-18)7-6-11-4-2-1-3-5-11/h1-5,8,10,12,18H,6-7,9H2,(H2,15,19) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| 5.90E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Addis Ababa University
Curated by ChEMBL
| Assay Description Inhibition of human ADA |
Bioorg Med Chem 15: 3728-36 (2007)
Article DOI: 10.1016/j.bmc.2007.03.048 BindingDB Entry DOI: 10.7270/Q21Z4433 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |