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SMILES: CN(CCCn1c(C)c(cc1-c1ccccc1)C(=O)Nc1cccc(c1)C(F)(F)F)C(=O)C1CCC1

InChI Key: InChIKey=JGZXCSQIMXBBQB-UHFFFAOYSA-N

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 230215   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily V member 4


(Homo sapiens (Human))		BDBM230215
PNG
(US9340500, I-059)
Show SMILES CN(CCCn1c(C)c(cc1-c1ccccc1)C(=O)Nc1cccc(c1)C(F)(F)F)C(=O)C1CCC1
Show InChI InChI=1S/C28H30F3N3O2/c1-19-24(26(35)32-23-14-7-13-22(17-23)28(29,30)31)18-25(20-9-4-3-5-10-20)34(19)16-8-15-33(2)27(36)21-11-6-12-21/h3-5,7,9-10,13-14,17-18,21H,6,8,11-12,15-16H2,1-2H3,(H,32,35)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
 472 -8.97n/an/an/an/an/an/a37



SHIONOGI & CO., LTD.

US Patent


Assay Description
Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...

US Patent US9340500 (2016)


BindingDB Entry DOI: 10.7270/Q2319TR3
More data for this
Ligand-Target Pair