BDBM230984 US9340549, 2

SMILES: CC1(C)OC(=O)N([C@H]1c1ccc(F)cc1)c1ccc(cc1)C(=O)Nc1cccc2cccnc12

InChI Key: InChIKey=XNFGHXBDRBTRQX-DEOSSOPVSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 230984   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tankyrase-1 (Homo sapiens (Human))	BDBM230984 (US9340549, 2) Show SMILES CC1(C)OC(=O)N([C@H]1c1ccc(F)cc1)c1ccc(cc1)C(=O)Nc1cccc2cccnc12 |r| Show InChI InChI=1S/C27H22FN3O3/c1-27(2)24(18-8-12-20(28)13-9-18)31(26(33)34-27)21-14-10-19(11-15-21)25(32)30-22-7-3-5-17-6-4-16-29-23(17)22/h3-16,24H,1-2H3,(H,30,32)/t24-/m0/s1	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	307	n/a	n/a	n/a	n/a	n/a	25
AMGEN INC. US Patent					Assay Description The tankyrase 1 biochemical activity of the compounds was assayed in the following assay buffer (50 mM MOPS pH7.5, 100 mM NaCl, 2.5 mM MgCl2, 0.01% T...				US Patent US9340549 (2016) BindingDB Entry DOI: 10.7270/Q2SN07VD
					More data for this Ligand-Target Pair