BDBM231049 US9340549, 69

SMILES: CC1(C)OC(=O)N([C@H]1c1ccccc1)c1ccc(cc1)-n1nnc2ccccc12

InChI Key: InChIKey=FEPMOIGAYQDZQG-NRFANRHFSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 231049   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tankyrase-1 (Homo sapiens (Human))	BDBM231049 (US9340549, 69) Show SMILES CC1(C)OC(=O)N([C@H]1c1ccccc1)c1ccc(cc1)-n1nnc2ccccc12 |r| Show InChI InChI=1S/C23H20N4O2/c1-23(2)21(16-8-4-3-5-9-16)26(22(28)29-23)17-12-14-18(15-13-17)27-20-11-7-6-10-19(20)24-25-27/h3-15,21H,1-2H3/t21-/m0/s1	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	25
AMGEN INC. US Patent					Assay Description The tankyrase 1 biochemical activity of the compounds was assayed in the following assay buffer (50 mM MOPS pH7.5, 100 mM NaCl, 2.5 mM MgCl2, 0.01% T...				US Patent US9340549 (2016) BindingDB Entry DOI: 10.7270/Q2SN07VD
					More data for this Ligand-Target Pair