BDBM231568 US9345700, 3

SMILES: Fc1ccccc1-c1ccc2nc(cc(C(=O)Nc3cccnc3)c2c1)-c1ccco1

InChI Key: InChIKey=TYBCDZWPKGHELV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 231568   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human))	BDBM231568 (US9345700, 3) Show SMILES Fc1ccccc1-c1ccc2nc(cc(C(=O)Nc3cccnc3)c2c1)-c1ccco1 Show InChI InChI=1S/C25H16FN3O2/c26-21-7-2-1-6-18(21)16-9-10-22-19(13-16)20(14-23(29-22)24-8-4-12-31-24)25(30)28-17-5-3-11-27-15-17/h1-15H,(H,28,30)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eutropics Pharmaceuticals, Inc. US Patent					Assay Description A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...				US Patent US9345700 (2016) BindingDB Entry DOI: 10.7270/Q2J38RD4
					More data for this Ligand-Target Pair