BDBM23167 (2R)-2-amino-3-hydroxypropanoic acid::CHEMBL285123::D-Serine

SMILES: N[C@H](CO)C(O)=O

InChI Key: InChIKey=MTCFGRXMJLQNBG-UWTATZPHSA-N

Data: 1 KI  1 IC50

PDB links: 133 PDB IDs match this monomer. 76 PDB IDs contain this monomer as substructures. 76 PDB IDs contain inhibitors having a similarity of 90% to this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 23167   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proton-coupled amino acid transporter 1 (Homo sapiens (Human))	BDBM23167 ((2R)-2-amino-3-hydroxypropanoic acid | CHEMBL28512...) Show SMILES N[C@H](CO)C(O)=O Show InChI InChI=1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	2.20E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther-University Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation counting				Bioorg Med Chem 19: 6409-18 (2011) Checked by Author Article DOI: 10.1016/j.bmc.2011.08.058 BindingDB Entry DOI: 10.7270/Q2NZ882D
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM23167 ((2R)-2-amino-3-hydroxypropanoic acid | CHEMBL28512...) Show SMILES N[C@H](CO)C(O)=O Show InChI InChI=1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	670	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description In vitro inhibitory activity of the compound to inhibit [3H]-glycine binding to NMDA receptor				Bioorg Med Chem Lett 9: 1409-14 (1999) BindingDB Entry DOI: 10.7270/Q2W0954Z
					More data for this Ligand-Target Pair				3D Structure (crystal)