BDBM234308 N-(2,4-dichlorophenyl)-2-hydroxybenzamide (9)
SMILES: Oc1ccccc1C(=O)Nc1ccc(Cl)cc1Cl
InChI Key: InChIKey=GFUKRQFBTHGSIC-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Epidermal growth factor receptor (EGFR) (Homo sapiens (Human)) | BDBM234308 (N-(2,4-dichlorophenyl)-2-hydroxybenzamide (9)) | PDB GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.53E+4 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Nanjing University | Assay Description Compounds 1-32 were dissolved in 100% DMSO and diluted to the appropriate concentrations with 25 mM HEPES at pH 7.4. In each well, 10 μL of comp... | J Enzyme Inhib Med Chem 26: 37-45 (2011) Article DOI: 10.3109/14756361003671060 BindingDB Entry DOI: 10.7270/Q2XW4HPN | |||||||||||
More data for this Ligand-Target Pair |