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BDBM234308 N-(2,4-dichlorophenyl)-2-hydroxybenzamide (9)

SMILES: Oc1ccccc1C(=O)Nc1ccc(Cl)cc1Cl

InChI Key: InChIKey=GFUKRQFBTHGSIC-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 234308   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Epidermal growth factor receptor (EGFR)


(Homo sapiens (Human))
BDBM234308
PNG
(N-(2,4-dichlorophenyl)-2-hydroxybenzamide (9))
Show SMILES Oc1ccccc1C(=O)Nc1ccc(Cl)cc1Cl
Show InChI InChI=1S/C13H9Cl2NO2/c14-8-5-6-11(10(15)7-8)16-13(18)9-3-1-2-4-12(9)17/h1-7,17H,(H,16,18)
PDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.53E+4n/an/an/an/a7.425



Nanjing University



Assay Description
Compounds 1-32 were dissolved in 100% DMSO and diluted to the appropriate concentrations with 25 mM HEPES at pH 7.4. In each well, 10 μL of comp...


J Enzyme Inhib Med Chem 26: 37-45 (2011)


Article DOI: 10.3109/14756361003671060
BindingDB Entry DOI: 10.7270/Q2XW4HPN
More data for this
Ligand-Target Pair