BindingDB logo
myBDB logout

null

SMILES: CCCC[C@@H](C(c1csc2c(cc(F)cc12)-c1ccnn1C)c1ccc(Cl)cc1)c1ccc(cc1)C(=O)NCCC(O)=O

InChI Key: InChIKey=AQUZMSQNDJPTEI-PSPFREQMSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 235125   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glucagon receptor


(Homo sapiens (Human))		BDBM235125
PNG
(US9359339, 2)
Show SMILES CCCC[C@@H](C(c1csc2c(cc(F)cc12)-c1ccnn1C)c1ccc(Cl)cc1)c1ccc(cc1)C(=O)NCCC(O)=O |r|
Show InChI InChI=1S/C34H33ClFN3O3S/c1-3-4-5-26(21-6-8-23(9-7-21)34(42)37-16-15-31(40)41)32(22-10-12-24(35)13-11-22)29-20-43-33-27(29)18-25(36)19-28(33)30-14-17-38-39(30)2/h6-14,17-20,26,32H,3-5,15-16H2,1-2H3,(H,37,42)(H,40,41)/t26-,32?/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 4.70n/an/an/an/a7.525



Merck Sharp & Dohme Corp.

US Patent


Assay Description
A stable CHO (Chinese hamster ovary) cell line expressing cloned human glucagon receptor was maintained as described (Chicchi, et. al. J Biol Chem 27...

US Patent US9359339 (2016)


BindingDB Entry DOI: 10.7270/Q2FQ9VHC
More data for this
Ligand-Target Pair