BDBM235134 US9359339, 21
SMILES: CCC[C@@H](C(c1csc2c(cc(Cl)cc12)C#N)c1ccc(Cl)c(Cl)c1)c1ccc(cc1)C(=O)NCCC(O)=O
InChI Key: InChIKey=DWAXSTCSXXYUEI-WZOMIXFGSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glucagon receptor (Homo sapiens (Human)) | BDBM235134 (US9359339, 21) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Merck Sharp & Dohme Corp. US Patent | Assay Description A stable CHO (Chinese hamster ovary) cell line expressing cloned human glucagon receptor was maintained as described (Chicchi, et. al. J Biol Chem 27... | US Patent US9359339 (2016) BindingDB Entry DOI: 10.7270/Q2FQ9VHC | |||||||||||
More data for this Ligand-Target Pair |