null

SMILES: FC(F)(F)CCCOc1ccc(cc1)[C@@]1(CC(c2ccn(CC3CC3)n2)=C(C(=O)NS(=O)(=O)C2CC2)C(=O)N1)C(F)(F)F

InChI Key: InChIKey=ZABFBNAJDMTMSF-VWLOTQADSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 235265   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM235265 (US9365558, 88 | US9822074, 88) Show SMILES FC(F)(F)CCCOc1ccc(cc1)[C@@]1(CC(c2ccn(CC3CC3)n2)=C(C(=O)NS(=O)(=O)C2CC2)C(=O)N1)C(F)(F)F |r,t:28| Show InChI InChI=1S/C27H28F6N4O5S/c28-26(29,30)11-1-13-42-18-6-4-17(5-7-18)25(27(31,32)33)14-20(21-10-12-37(35-21)15-16-2-3-16)22(23(38)34-25)24(39)36-43(40,41)19-8-9-19/h4-7,10,12,16,19H,1-3,8-9,11,13-15H2,(H,34,38)(H,36,39)/t25-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The MGAT enzyme reactions were performed in Corning FALCON® 96-well Polypropylene plates, in a total volume of 60 μL of 50 mM Potassium Phosphat...				US Patent US9822074 (2017) BindingDB Entry DOI: 10.7270/Q2K939TM
					More data for this Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM235265 (US9365558, 88 | US9822074, 88) Show SMILES FC(F)(F)CCCOc1ccc(cc1)[C@@]1(CC(c2ccn(CC3CC3)n2)=C(C(=O)NS(=O)(=O)C2CC2)C(=O)N1)C(F)(F)F |r,t:28| Show InChI InChI=1S/C27H28F6N4O5S/c28-26(29,30)11-1-13-42-18-6-4-17(5-7-18)25(27(31,32)33)14-20(21-10-12-37(35-21)15-16-2-3-16)22(23(38)34-25)24(39)36-43(40,41)19-8-9-19/h4-7,10,12,16,19H,1-3,8-9,11,13-15H2,(H,34,38)(H,36,39)/t25-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	67	n/a	n/a	n/a	n/a	7.4	65
Bristol-Myers Squibb Company US Patent					Assay Description The MGAT enzyme reactions were performed in Corning FALCON® 96-well Polypropylene plates, in a total volume of 60 μL of 50 mM Potassium Phosph...				US Patent US9365558 (2016) BindingDB Entry DOI: 10.7270/Q2XS5T8B
					More data for this Ligand-Target Pair