null

SMILES: CNC(=O)c1c(oc2cc(N(C)S(C)(=O)=O)c(cc12)-c1ccc2OCN(C(C)c3ccc(F)cc3)C(=O)c2n1)-c1ccc(F)cc1

InChI Key: InChIKey=WBABIWUULPNBAQ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 235856   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Genome polyprotein [1027-1711] (Hepatitis C virus genotype 1b (isolate BK) (HCV))	BDBM235856 (US9364482, 30) Show SMILES CNC(=O)c1c(oc2cc(N(C)S(C)(=O)=O)c(cc12)-c1ccc2OCN(C(C)c3ccc(F)cc3)C(=O)c2n1)-c1ccc(F)cc1 |@@:25| Show InChI InChI=1S/C33H28F2N4O6S/c1-18(19-5-9-21(34)10-6-19)39-17-44-27-14-13-25(37-30(27)33(39)41)23-15-24-28(16-26(23)38(3)46(4,42)43)45-31(29(24)32(40)36-2)20-7-11-22(35)12-8-20/h5-16,18H,17H2,1-4H3,(H,36,40)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.23	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description Stable neomycin phosphotransferase encoding replicons-harboring cell lines were used, so all cell lines were maintained under G418 selection prior to...				US Patent US9364482 (2016) BindingDB Entry DOI: 10.7270/Q2TT4PVB
					More data for this Ligand-Target Pair
Genome polyprotein [1027-1711] (Hepatitis C virus genotype 1a (strain H77) (HCV))	BDBM235856 (US9364482, 30) Show SMILES CNC(=O)c1c(oc2cc(N(C)S(C)(=O)=O)c(cc12)-c1ccc2OCN(C(C)c3ccc(F)cc3)C(=O)c2n1)-c1ccc(F)cc1 |@@:25| Show InChI InChI=1S/C33H28F2N4O6S/c1-18(19-5-9-21(34)10-6-19)39-17-44-27-14-13-25(37-30(27)33(39)41)23-15-24-28(16-26(23)38(3)46(4,42)43)45-31(29(24)32(40)36-2)20-7-11-22(35)12-8-20/h5-16,18H,17H2,1-4H3,(H,36,40)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.981	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description Stable neomycin phosphotransferase encoding replicons-harboring cell lines were used, so all cell lines were maintained under G418 selection prior to...				US Patent US9364482 (2016) BindingDB Entry DOI: 10.7270/Q2TT4PVB
					More data for this Ligand-Target Pair