BDBM235926 US9365511, 27
SMILES: COC(=O)CNC(=O)C1(CCCC1)c1ccc(cc1)-c1ccc(CCN2CCC[C@H]2C)cc1
InChI Key: InChIKey=FIZIVORSAICWCM-OAQYLSRUSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Histamine H3 receptor (Homo sapiens (Human)) | BDBM235926![]() (US9365511, 27) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
ARENA PHARMACEUTICALS, INC. US Patent | Assay Description Compounds of the present invention were evaluated using the human H3 receptor (H3R) HTRF cAMP assay. In this assay, HEK293 cells expressing the human... | US Patent US9365511 (2016) BindingDB Entry DOI: 10.7270/Q2FJ2FP8 | |||||||||||
More data for this Ligand-Target Pair |