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SMILES: C[C@@H]1CCCN1CCc1ccc(cc1)-c1ccc(cc1)C1(CCCC1)C(=O)NCCCC(O)=O

InChI Key: InChIKey=UZMAISKCFMDEAX-JOCHJYFZSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 235927   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H3 receptor


(Homo sapiens (Human))		BDBM235927
PNG
(US9365511, 33)
Show SMILES C[C@@H]1CCCN1CCc1ccc(cc1)-c1ccc(cc1)C1(CCCC1)C(=O)NCCCC(O)=O |r|
Show InChI InChI=1S/C29H38N2O3/c1-22-6-5-20-31(22)21-16-23-8-10-24(11-9-23)25-12-14-26(15-13-25)29(17-2-3-18-29)28(34)30-19-4-7-27(32)33/h8-15,22H,2-7,16-21H2,1H3,(H,30,34)(H,32,33)/t22-/m1/s1
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US Patent
n/an/a 2.10n/an/an/an/an/an/a



ARENA PHARMACEUTICALS, INC.

US Patent


Assay Description
Compounds of the present invention were evaluated using the human H3 receptor (H3R) HTRF cAMP assay. In this assay, HEK293 cells expressing the human...

US Patent US9365511 (2016)


BindingDB Entry DOI: 10.7270/Q2FJ2FP8
More data for this
Ligand-Target Pair