BDBM236524 2-Methoxy-10-[(2-N,N-dimethylamino-2-methyl)ethyl)]benzo[d]isothiazolo[3,2-a]indol-S,S-dioxide (15)

SMILES: COc1ccc2C3C(=C(CC(C)N(C)C)c2c1)c1ccccc1S3(=O)=O

InChI Key: InChIKey=PSQWODHSSQQGEZ-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 236524   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM236524 ( 2-Methoxy-10-[(2-N,N-dimethylamino-2-methyl)ethyl...) Show SMILES COc1ccc2C3C(=C(CC(C)N(C)C)c2c1)c1ccccc1S3(=O)=O |t:7| Show InChI InChI=1S/C21H23NO3S/c1-13(22(2)3)11-18-17-12-14(25-4)9-10-15(17)21-20(18)16-7-5-6-8-19(16)26(21,23)24/h5-10,12-13,21H,11H2,1-4H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	11.6	-11.3	n/a	n/a	n/a	n/a	n/a	7.4	37
Suven Life Sciences Ltd.					Assay Description In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...				J Enzyme Inhib Med Chem 27: 443-50 (2012) Article DOI: 10.3109/14756366.2011.595713 BindingDB Entry DOI: 10.7270/Q2HD7TJ5
					More data for this Ligand-Target Pair