BDBM236529 2-Cyclohexylmethyloxy-10-[(2-N,N-dimethylamino-2-methyl)ethyl]benzo[d] isothiazolo[3,2-a]indol-S,S-dioxide (20)

SMILES: CC(CC1=C2C(c3ccc(OCC4CCCCC4)cc13)S(=O)(=O)c1ccccc21)N(C)C

InChI Key: InChIKey=RLDZYTBAMQXYOE-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 236529   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM236529 (2-Cyclohexylmethyloxy-10-[(2-N,N-dimethylamino-2-m...) Show SMILES CC(CC1=C2C(c3ccc(OCC4CCCCC4)cc13)S(=O)(=O)c1ccccc21)N(C)C |t:3| Show InChI InChI=1S/C27H33NO3S/c1-18(28(2)3)15-24-23-16-20(31-17-19-9-5-4-6-10-19)13-14-21(23)27-26(24)22-11-7-8-12-25(22)32(27,29)30/h7-8,11-14,16,18-19,27H,4-6,9-10,15,17H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>1.00E+3	>-8.51	n/a	n/a	n/a	n/a	n/a	7.4	37
Suven Life Sciences Ltd.					Assay Description In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...				J Enzyme Inhib Med Chem 27: 443-50 (2012) Article DOI: 10.3109/14756366.2011.595713 BindingDB Entry DOI: 10.7270/Q2HD7TJ5
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