BDBM238808 US9394297, 495

SMILES: C[C@H]1NC(=O)c2cc([nH]c12)-c1c(F)ccc2CN(C3CC3)C(NC3(C)CC3)=Nc12

InChI Key: InChIKey=UWSPFENPUCOTKU-LLVKDONJSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 238808   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM238808 (US9394297, 495) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1c(F)ccc2CN(C3CC3)C(NC3(C)CC3)=Nc12 |c:30| Show InChI InChI=1S/C22H24FN5O/c1-11-18-14(20(29)24-11)9-16(25-18)17-15(23)6-3-12-10-28(13-4-5-13)21(26-19(12)17)27-22(2)7-8-22/h3,6,9,11,13,25H,4-5,7-8,10H2,1-2H3,(H,24,29)(H,26,27)/t11-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0600	n/a	n/a	n/a	n/a	7.0	22
AMGEN INC. US Patent					Assay Description The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...				US Patent US9394297 (2016) BindingDB Entry DOI: 10.7270/Q2G44P78
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM238808 (US9394297, 495) Show SMILES C[C@H]1NC(=O)c2cc([nH]c12)-c1c(F)ccc2CN(C3CC3)C(NC3(C)CC3)=Nc12 |c:30| Show InChI InChI=1S/C22H24FN5O/c1-11-18-14(20(29)24-11)9-16(25-18)17-15(23)6-3-12-10-28(13-4-5-13)21(26-19(12)17)27-22(2)7-8-22/h3,6,9,11,13,25H,4-5,7-8,10H2,1-2H3,(H,24,29)(H,26,27)/t11-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0460	n/a	n/a	n/a	n/a	7.0	22
AMGEN INC. US Patent					Assay Description The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...				US Patent US9394297 (2016) BindingDB Entry DOI: 10.7270/Q2G44P78
					More data for this Ligand-Target Pair