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BDBM238955 US9403831, 46

SMILES: CC(=O)N1CCN(Cc2ccc(cc2)-c2cnc(nc2)N2CCCC(Cn3nnc4ncc(nc34)-c3cnn(C)c3)C2)CC1

InChI Key: InChIKey=PYFMYJADIZTTGB-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 238955   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM238955
PNG
(US9403831, 46)
Show SMILES CC(=O)N1CCN(Cc2ccc(cc2)-c2cnc(nc2)N2CCCC(Cn3nnc4ncc(nc34)-c3cnn(C)c3)C2)CC1
Show InChI InChI=1S/C31H36N12O/c1-22(44)41-12-10-40(11-13-41)18-23-5-7-25(8-6-23)26-14-33-31(34-15-26)42-9-3-4-24(19-42)20-43-30-29(37-38-43)32-17-28(36-30)27-16-35-39(2)21-27/h5-8,14-17,21,24H,3-4,9-13,18-20H2,1-2H3
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PC cid
PC sid
UniChem
US Patent
n/an/a 7n/an/an/an/an/a25



KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY; HANDOK INC.

US Patent


Assay Description
The c-Met kinase inhibitory activity was analyzed using dissociation enhanced lanthanide fluoro-immunoassay (DELFIA, Perkin Elmer), which is a kind o...

US Patent US9403831 (2016)


BindingDB Entry DOI: 10.7270/Q2TD9W7H
More data for this
Ligand-Target Pair