BDBM239657 US9394309, 113
SMILES: Cc1cc(C)c(cc1NC(=O)c1cc(Br)cc(c1)C(C)(C)C)-n1ccn2nc(cc12)-c1cccnc1
InChI Key: InChIKey=DBFQLWXYGASEET-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosine-protein kinase receptor TIE-2 (Homo sapiens (Human)) | BDBM239657 (US9394309, 113) | PDB GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Bayer Pharma Aktiengesellschaft; Bayer Intellectual Property GmbH US Patent | Assay Description For the assay, 50 nl of a 100-fold concentrated solution of the respective test substance in DMSO were pipetted into a black low-volume 384-well micr... | US Patent US9394309 (2016) BindingDB Entry DOI: 10.7270/Q2C53JRC | |||||||||||
More data for this Ligand-Target Pair |