BDBM239698 US9394309, 155

SMILES: COCCOCc1cc(cc(c1)S(F)(F)(F)(F)F)C(=O)Nc1cc(c(C)cc1C)-n1ccn2nc(cc12)-c1cccnc1

InChI Key: InChIKey=SGIDHWKWFGMQTI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 239698   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase receptor TIE-2 (Homo sapiens (Human))	BDBM239698 (US9394309, 155) Show SMILES COCCOCc1cc(cc(c1)S(F)(F)(F)(F)F)C(=O)Nc1cc(c(C)cc1C)-n1ccn2nc(cc12)-c1cccnc1 Show InChI InChI=1S/C29H28F5N5O3S/c1-19-11-20(2)27(38-7-8-39-28(38)16-26(37-39)22-5-4-6-35-17-22)15-25(19)36-29(40)23-12-21(18-42-10-9-41-3)13-24(14-23)43(30,31,32,33)34/h4-8,11-17H,9-10,18H2,1-3H3,(H,36,40)	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.700	n/a	n/a	n/a	n/a	7.0	22
Bayer Pharma Aktiengesellschaft; Bayer Intellectual Property GmbH US Patent					Assay Description For the assay, 50 nl of a 100-fold concentrated solution of the respective test substance in DMSO were pipetted into a black low-volume 384-well micr...				US Patent US9394309 (2016) BindingDB Entry DOI: 10.7270/Q2C53JRC
					More data for this Ligand-Target Pair