null

SMILES: Fc1ccc(Nc2ccc(c(c2)C(F)(F)F)S(=O)(=O)NCC2CC2)c(F)c1

InChI Key: InChIKey=SDRWZARPOTZJEG-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 242460   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM242460 (US9422235, 36) Show SMILES Fc1ccc(Nc2ccc(c(c2)C(F)(F)F)S(=O)(=O)NCC2CC2)c(F)c1 Show InChI InChI=1S/C17H15F5N2O2S/c18-11-3-5-15(14(19)7-11)24-12-4-6-16(13(8-12)17(20,21)22)27(25,26)23-9-10-1-2-10/h3-8,10,23-24H,1-2,9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	53	-10.1	106	n/a	n/a	n/a	n/a	n/a	30
Pharmos Corporation US Patent					Assay Description The binding assays were performed by testing the ability of the new compounds to displace the radiolabeled synthetic non-selective cannabinoid agonis...				US Patent US9422235 (2016) BindingDB Entry DOI: 10.7270/Q2833QX2
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM242460 (US9422235, 36) Show SMILES Fc1ccc(Nc2ccc(c(c2)C(F)(F)F)S(=O)(=O)NCC2CC2)c(F)c1 Show InChI InChI=1S/C17H15F5N2O2S/c18-11-3-5-15(14(19)7-11)24-12-4-6-16(13(8-12)17(20,21)22)27(25,26)23-9-10-1-2-10/h3-8,10,23-24H,1-2,9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	66	-9.95	132	n/a	n/a	n/a	n/a	n/a	30
Pharmos Corporation US Patent					Assay Description The binding assays were performed by testing the ability of the new compounds to displace the radiolabeled synthetic non-selective cannabinoid agonis...				US Patent US9422235 (2016) BindingDB Entry DOI: 10.7270/Q2833QX2
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM242460 (US9422235, 36) Show SMILES Fc1ccc(Nc2ccc(c(c2)C(F)(F)F)S(=O)(=O)NCC2CC2)c(F)c1 Show InChI InChI=1S/C17H15F5N2O2S/c18-11-3-5-15(14(19)7-11)24-12-4-6-16(13(8-12)17(20,21)22)27(25,26)23-9-10-1-2-10/h3-8,10,23-24H,1-2,9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	68	-9.94	132	n/a	n/a	n/a	n/a	n/a	30
Pharmos Corporation US Patent					Assay Description The binding assays were performed by testing the ability of the new compounds to displace the radiolabeled synthetic non-selective cannabinoid agonis...				US Patent US9422235 (2016) BindingDB Entry DOI: 10.7270/Q2833QX2
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM242460 (US9422235, 36) Show SMILES Fc1ccc(Nc2ccc(c(c2)C(F)(F)F)S(=O)(=O)NCC2CC2)c(F)c1 Show InChI InChI=1S/C17H15F5N2O2S/c18-11-3-5-15(14(19)7-11)24-12-4-6-16(13(8-12)17(20,21)22)27(25,26)23-9-10-1-2-10/h3-8,10,23-24H,1-2,9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	131	-9.54	215	n/a	n/a	n/a	n/a	n/a	30
Pharmos Corporation US Patent					Assay Description The binding assays were performed by testing the ability of the new compounds to displace the radiolabeled synthetic non-selective cannabinoid agonis...				US Patent US9422235 (2016) BindingDB Entry DOI: 10.7270/Q2833QX2
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM242460 (US9422235, 36) Show SMILES Fc1ccc(Nc2ccc(c(c2)C(F)(F)F)S(=O)(=O)NCC2CC2)c(F)c1 Show InChI InChI=1S/C17H15F5N2O2S/c18-11-3-5-15(14(19)7-11)24-12-4-6-16(13(8-12)17(20,21)22)27(25,26)23-9-10-1-2-10/h3-8,10,23-24H,1-2,9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	822	-8.43	1.93E+3	n/a	n/a	n/a	n/a	n/a	30
Pharmos Corporation US Patent					Assay Description The binding assays were performed by testing the ability of the new compounds to displace the radiolabeled synthetic non-selective cannabinoid agonis...				US Patent US9422235 (2016) BindingDB Entry DOI: 10.7270/Q2833QX2
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM242460 (US9422235, 36) Show SMILES Fc1ccc(Nc2ccc(c(c2)C(F)(F)F)S(=O)(=O)NCC2CC2)c(F)c1 Show InChI InChI=1S/C17H15F5N2O2S/c18-11-3-5-15(14(19)7-11)24-12-4-6-16(13(8-12)17(20,21)22)27(25,26)23-9-10-1-2-10/h3-8,10,23-24H,1-2,9H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.00E+3	-7.66	6.00E+3	n/a	n/a	n/a	n/a	n/a	30
Pharmos Corporation US Patent					Assay Description The binding assays were performed by testing the ability of the new compounds to displace the radiolabeled synthetic non-selective cannabinoid agonis...				US Patent US9422235 (2016) BindingDB Entry DOI: 10.7270/Q2833QX2
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM242460 (US9422235, 36) Show SMILES Fc1ccc(Nc2ccc(c(c2)C(F)(F)F)S(=O)(=O)NCC2CC2)c(F)c1 Show InChI InChI=1S/C17H15F5N2O2S/c18-11-3-5-15(14(19)7-11)24-12-4-6-16(13(8-12)17(20,21)22)27(25,26)23-9-10-1-2-10/h3-8,10,23-24H,1-2,9H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.27E+3	-7.60	5.95E+3	n/a	n/a	n/a	n/a	n/a	30
Pharmos Corporation US Patent					Assay Description The binding assays were performed by testing the ability of the new compounds to displace the radiolabeled synthetic non-selective cannabinoid agonis...				US Patent US9422235 (2016) BindingDB Entry DOI: 10.7270/Q2833QX2
					More data for this Ligand-Target Pair