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SMILES: FC(F)(F)c1cccc(n1)C(=O)Nc1cccc(CN2CCC(CC2)C(=O)NC2CCCC2)c1

InChI Key: InChIKey=UPNCHJIULVXTQB-UHFFFAOYSA-N

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 243779   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Atypical chemokine receptor 3


(Homo sapiens (Human))		BDBM243779
PNG
(US9428456, 1.208)
Show SMILES FC(F)(F)c1cccc(n1)C(=O)Nc1cccc(CN2CCC(CC2)C(=O)NC2CCCC2)c1
Show InChI InChI=1S/C25H29F3N4O2/c26-25(27,28)22-10-4-9-21(31-22)24(34)30-20-8-3-5-17(15-20)16-32-13-11-18(12-14-32)23(33)29-19-6-1-2-7-19/h3-5,8-10,15,18-19H,1-2,6-7,11-14,16H2,(H,29,33)(H,30,34)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.600n/an/an/a37



ACTELION PHARMACEUTICALS LTD

US Patent


Assay Description
CHO-K1 CXCR7 b-arrestin cells are detached from culture dishes with a cell dissociation buffer (Invitrogen, #13151-014) and collected in growing medi...

US Patent US9428456 (2016)


BindingDB Entry DOI: 10.7270/Q29022PZ
More data for this
Ligand-Target Pair