BDBM244094 US9428478, TG6-254-2

SMILES: CNC(=O)c1ccc2[nH]c(cc2c1)C(=O)N1CCN(CC1)c1ccc(OC)c(F)c1

InChI Key: InChIKey=VHUPVSUMJAHLGS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 244094   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome b-245 heavy chain (Homo sapiens (Human))	BDBM244094 (US9428478, TG6-254-2) Show SMILES CNC(=O)c1ccc2[nH]c(cc2c1)C(=O)N1CCN(CC1)c1ccc(OC)c(F)c1 Show InChI InChI=1S/C22H23FN4O3/c1-24-21(28)14-3-5-18-15(11-14)12-19(25-18)22(29)27-9-7-26(8-10-27)16-4-6-20(30-2)17(23)13-16/h3-6,11-13,25H,7-10H2,1-2H3,(H,24,28)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.00E+10	n/a	n/a	n/a	n/a	n/a	n/a
Emory University US Patent					Assay Description Nox2 activity assay for primary screening: Plasma membranes were prepared from human neutrophils, which express large amounts of Nox2, stored at W...				US Patent US9428478 (2016) BindingDB Entry DOI: 10.7270/Q2RX9B09
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