BDBM245168 US9428460, 24
SMILES: Fc1ccc(cc1F)C(=O)N[C@H]1CC[C@@H](CC1)Oc1ccnc2c(cccc12)C#N
InChI Key: InChIKey=PLHTVJLVFPNJAL-QAQDUYKDSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Androgen receptor (AR) (Homo sapiens (Human)) | BDBM245168 (US9428460, 24) | PDB GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 92 | n/a | n/a | n/a | n/a | n/a | 37 |
BAYER PHARMA AKTIENGESELLSCHAFT US Patent | Assay Description For determining the androgen receptor-dependent transcription, a cellular assay system was used, consisting of PC-3 cells (Kaighn et al., Invest. Uro... | US Patent US9428460 (2016) BindingDB Entry DOI: 10.7270/Q25719Z7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (E709Y) (Homo sapiens (Human)) | BDBM245168 (US9428460, 24) | PDB GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | 37 |
BAYER PHARMA AKTIENGESELLSCHAFT US Patent | Assay Description PC-3 cells (Kaighn et al., Invest. Urol. 17: 16-23, 1979) were plated out at a density of 10000 cells per well of a 96-well cell culture plate in RMP... | US Patent US9428460 (2016) BindingDB Entry DOI: 10.7270/Q25719Z7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (W741C) (Homo sapiens (Human)) | BDBM245168 (US9428460, 24) | PDB GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 72 | n/a | n/a | n/a | n/a | n/a | 37 |
BAYER PHARMA AKTIENGESELLSCHAFT US Patent | Assay Description PC-3 cells (Kaighn et al., Invest. Urol. 17: 16-23, 1979) were plated out at a density of 10000 cells per well of a 96-well cell culture plate in RMP... | US Patent US9428460 (2016) BindingDB Entry DOI: 10.7270/Q25719Z7 | |||||||||||
More data for this Ligand-Target Pair |